“A scientific truth does not triumph by convincing its opponents and making them see the light, but rather because its opponents eventually die and a new generation grows up that is familiar with it.”

--Max Planck

The beginning of the new millennium was marked by rapid advances in genome sequencing combined with an unprecedented development of novel research approaches to study biological systems in their complexity. A vast amount of genomic information and new tools triggered a major shift in the scientific paradigm, switching from the traditional “hypothesis testing” approach to a broader experimental design that included a prerequisite and more extensive “hypothesis generation” steps logically connected with follow-up functional studies. These changes created a whole new field of research generally referred to as Functional Genomics.

The research in our lab applies the tools and techniques of Functional Genomics to the study of human neurological diseases. It focuses on generating whole genome expression data in health and disease often referred to as “fishing expeditions”, and filtering these data using functional studies in vitro and in vivo towards the identification of novel drug candidates or disease biomarkers as a final goal.

Los Angeles Biomedical Research Institute

This website was inspired by Dr. Mirnic's Bistro.